Endocrine Abstracts

The Women's Health Initiative (WHI) trial and Million Women's Study (MWS) fundamentally changed our understanding of risks and benefits associated with HRT. WHI for the first time provided evidence of harmful effects of HRT on the cardiovascular system and also confirmed significantly increased risk of breast cancer previously documented in a meta analysis. HRT does not decrease, and may in fact increase, the incidence of ishaemic heart disease. The risk of stroke is increased...